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KMID : 0358419940370102104
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Korean Journal of Obstetrics and Gynecology
1994 Volume.37 No. 10 p.2104 ~ p.2109
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A Case of Post-Transfusion Purpura
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차용재
김준길/김준태/김태수/신영관/김동진
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Abstract
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Post-transfusion purpura(PTP) is believed to be a rare clinical syndrome characterized by the acute occurrence of severe purpura with thrombocytopenia approximately 1 week after blood transfusion. This syndrome occurs predominantly in patients
who
lack
the platelet-specific alloantigen, and has been previously sensitized by prior transfusion or pregnancy. The typical patient is a middle-aged, multiparous white woman. Diagnosis may be suspected by normal clotting studies, bone marrow biopsy
showing
increased megakaryocytes, and demonstration of a potent antibody reactive against platelets by appropriate serologic tests. Treatment with corticosteroid and platelet transfusion is ineffective. Exchange thansfusion or plasmapheresis has led to
improved
survival in this disease. Recent reports indicate that IV IgG may become a effective treatment. We exprienced a case of PTP in a multiparous woman received first blood transfusion during Cesarean section. Here we report this case with brief
review
of
literature.
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KEYWORD
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